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CAS 62-44-2 Phenacetin Shyigikira uburyo butandukanye bwo kwishyura

CAS 62-44-2 Phenacetin Shyigikira uburyo butandukanye bwo kwishyura Kugaragaza Ishusho
  • CAS 62-44-2 Phenacetin Shyigikira uburyo butandukanye bwo kwishyura
  • CAS 62-44-2 Phenacetin Shyigikira uburyo butandukanye bwo kwishyura
  • CAS 62-44-2 Phenacetin Shyigikira uburyo butandukanye bwo kwishyura
  • CAS 62-44-2 Phenacetin Shyigikira uburyo butandukanye bwo kwishyura
  • CAS 62-44-2 Phenacetin Shyigikira uburyo butandukanye bwo kwishyura

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    • Ibicuruzwa birambuye

    Ibicuruzwa

    62-44-2

    Izina Rusange Phenacetin
    Umubare CAS 62-44-2 Uburemere bwa molekile 179.216
    Ubucucike 1.0 ± 0.1 g / cm3 Ingingo 323.6 ± 44.0 ° C kuri 760 mmHg
    Inzira ya molekulari C10H13NO2 Ingingo yo gushonga 133-136 ° C (lit.)
    MSDS Igishinwa Amerika Flash point 149.5 ± 28.4 ° C.
    Ikimenyetso hfg

    GHS07, GHS08

    		 Ijambo ry'ikimenyetso Akaga

    62-44-2 (5)

    62-44-2 (4)

    62-44-2 (3)

    62-44-2 (2)

    62-44-2 (1)
    gupakira (4) gupakira (2)

    Gukoresha Phenacetin

    Phenacetin ni analgesic idafite opioid idafite imiti igabanya ubukana, ibuza ibikorwa bya COX-3. Intego: COXPhenacetin ni imiti igabanya ububabare kandi igabanya umuriro, Phenacetin yakuwe ku isoko rya Kanada muri Kamena 1973 kubera impungenge zatewe na nepropatique.amakuru y’amavuriro na laboratoire yahujwe na "phenacetin nephritis" nkuko byasobanuwe mu Burayi no muri Ositaraliya ndetse no muri Amerika na Kanada.Iyi raporo isuzuma ibyagaragaye mu manza 23 kandi ikanaburira kwirinda ikoreshwa rya phenacetine, cyane cyane ku barwayi bafite ikibazo cy’impyiko [1].Phenacetin yahujwe na nérosose papillary neprosis mu bantu [2, 3].

    Igikorwa cyibinyabuzima cya Phenacetin

    Ibisobanuro Phenacetin ni analgesic idafite opioid idafite imiti igabanya ubukana, ibuza ibikorwa bya COX-3. Intego: COXPhenacetin ni imiti igabanya ububabare kandi igabanya umuriro, Phenacetin yakuwe ku isoko rya Kanada muri Kamena 1973 kubera impungenge zatewe na nepropatique.amakuru y’amavuriro na laboratoire yahujwe na "phenacetin nephritis" nkuko byasobanuwe mu Burayi no muri Ositaraliya ndetse no muri Amerika na Kanada.Iyi raporo isuzuma ibyagaragaye mu manza 23 kandi ikanaburira kwirinda ikoreshwa rya phenacetine, cyane cyane ku barwayi bafite ikibazo cy’impyiko [1].Phenacetine yahujwe na nérosose papillary neprosis mu bantu [2, 3].
    Cataloge bifitanye isano
    Ibice byubushakashatsi >> Gutwika / Gukingira
    Intego COX-3: 102 μM (IC50)
    Umuti
    Muri Vitro:

    MM 10 muri DMSO
    Gukemura
    1 mM 5.5797 mL 27.8987 mL 55.7973 mL
    5 mM 1.1159 mL 5.5797 mL 11.1595 mL
    10 mM 0.5580 mL 2.7899 mL 5.5797 mL
    Ububiko
    Ifu -20 ° C. Imyaka 3
    4 ° C. Imyaka 2
    Mubishobora -80 ° C. Amezi 6
    -20 ° C. Ukwezi 1
    Kohereza Ubushyuhe bwicyumba kumugabane wa Amerika;Birashobora gutandukana ahandi
    URWENYA CC (NC1 = CC = C (OCC) C = C1) = O.
    Reba [1].Chandrasekharan NV, n'abandi.COX-3, cyclooxygenase-1 ihagarikwa na acetaminofeni nindi miti ya analgesic / antipyretic: cloni, imiterere, nimvugo.Inzira Natl Acad Sci US A. 2002 Ukwakira 15; 99 (21): 13926-31. [2]Brix, AE, impyiko ya papillary necrosis.Inzira ya Toxicol, 2002. 30 (6): p.672-4.

    [3].Dubach, UC, B. Rosner, na T. Sturmer, Ubushakashatsi bwakozwe na epidemiologique yo gukoresha nabi imiti idakira.Ingaruka za phenacetine na salicylate ku rupfu n'indwara z'umutima n'imitsi (1968 kugeza 1987).N Engl J Med, 1991. 324 (3): p.155-60.
    Ibijyanye na molekile 4-Acetamidophenol |Aspirin |Paradol |Ginsenoside Rg3 |Ginsenoside CK |Xanthohumol |Ibuprofen |Diclofenac |NS-398 |Meloxicam |Acide Flufenamic |(-) - Epicatechin |Acide Salicylic |ketoprofen |Naproxen

    Synonyme

    MFCD00009094
    Acetamide, N- (4-ethoxyphenyl) - (9CI)
    N- (4-ethoxyphenyl) -acetamide
    P-PHENACETIN
    Acide Ethanimidic, N- (4-ethoxyphenyl) -, (1E) -
    Achrocidin
    p-ethoxyacetanilide
    phenacetin
    Fenacetine
    phenacitin
    Codempiral
    Acetphenetidin
    ACETOPHENETIDIN
    Kurwanya
    Acetophenetidine
    Fenacetina
    Acetophenetin
    N- (4-Ethoxyphenyl) acetamide
    (1E) -N- (4-Ethoxyphenyl) aside aside ya Ethanimidic
    N-acetyl-p-phenetidine
    p-Acetophenetidide
    Acetamide, N- (4-ethoxyphenyl) -
    N- (4-ethoxyphenol) acetamide
    Acetamide, N- (4-ethoxyphenol) -
    Aceto-p-phenetidin
    EINECS 200-533-0
    4'-ethoxyacetanilide
    N- [4- (Ethyloxy) fenyl] acetamide
    N-Acetyl-para-phenetidine
    Acetanilide, 4'-ethoxy-
    N-Acetyl-4-ethoxyaniline

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